Well, Nanc, the good thing is that certain things are being ruled/out of this mix and they seem to be on the trail to finding what will work.
I sure hope you can find a cocktail of meds that will get these headaches under control.
I think I am the same way with my Hydrocodone as you are with your Topomax. It's getting less and less effective as my tolerance continues to go up.
Rae