Jasmine, I just wanted to mention that my son had very adverse reactions to meds when we initially tried those and yes, part of those side effects were severe impacts on his mood and general psyche. Once he stopped the meds, things really improved in that area.
Although clonidine is generally not known for intense side effects, I do know of it having psychotic reactions in some people. So it may be the meds causing those mood swings.
Whatever it is, it really sounds like perhaps you getting a asecond opinion on it all may be a good idea...the fact that your doctor felt botox was the only real solution is a bit troubling to me!

If you can, try to find an Integrative doctor who has experience with TS. Integrative docs are ones that are fully qualified in conventional medicine (MD or DO) but have gone on to also specialize in alternative/naturopathic medicine and so they have a far more holistic approach.