I once took 5HTP as recommended by a book that my naturopath recommended, half an hour later I was throwing up. So I'm sure this is very complicated to get everything in the right balance - kind of discouraging actually as I have no idea where to find a medical practitioner who could or would monitor this for me.

My MDS is on sick leave, and another one in his practise has been trying to help me sort out my nighttime aching and sleep disturbance - my latest move is supposed to be taking one and then two 100/25 Sinemet CR at bedtime, that's a pretty big increase over the five regular ones I take spread out through the day now. I really wish I could find something that would slow this down a little, don't we all.

Has anyone switched from regular Mirapex to extended release Mirapex? Did it help smooth things out?