Hello Hannah, this is the first I have heard concerning Topamax and RSD. I am new to neurotalk and haven't read all there is to read. I am not new to RSD or Topamax though. I was diagnosed with RSD maybe a little over three years ago, but I was already taking Topamax for my history of chronic migraines. I do however have a question; have you experienced and hair loss while taking Topamax. Also I haven't notice any difference in my pain since my dosage has been increased.