I haven't taken both AT THE SAME TIME, but I've taken both. The Opana didn't work well for me --- I didn't get much pain relief at all from it. Right now I'm on Methadone, and it seems to work better. The only problem I'm having now is the dosage. At first, it was ok, but now after having been on it for so long, I need an increase and i've asked my doc for one, but he doesn't seem to want to do it. I'm also on the Fentanyl Patch.

I'm on only 10mg of Methadone 3 times a day, which is ridiculous! I'm on .75mcg of Fentanyl Patch, and even THAT needs increasing, but he just won't listen. The last several days I've been in agony -- don't know if I did something or what. But this pain is about to drive me nuts!

I wish you the best of luck. I hope your pain lessens -- or your doc adjusts your medication! God bless & please take care. Hugs, Lee