I have PN and am up to 60mg Oxycotin ER ever 6 hrs. amounting to 240mg's of Oxycotin ER daily. Also take Oxycodone (percocet) 7.5-323 up to 4 times a day for breakthru. I do take a 5 mg. two times a day with the Oxycodone. I am hyper, but not sure because so many things do that to me, including pain. I at first blamed the Oxycotin; but I notice as my pain increases; I get even more hyper and can't seem to stop talking. I even had that reaction to the R-lipoic acid.

I tried Opana a while back and it didn't do much for my pain and went back to the Oxycotin ER.