Originally Posted by Dr. Smith

What I get that says, which appears to have been considerably altered from the original:
http://en.wikipedia.org/wiki/Buprenorphine
is that the butrans would be the cause of cognitive and memory deficiencies by blocking the endogenous endorphins from binding to the receptors - not the percocet.

Oxycodone has some deliterious effects on some few patients, but generally with opioid-naive patients. More often it may have euphoric/calming effects, which wear off in time, (would be blocked by the butrans) and would not be likely with a patient who has taken percocet for a very long time.

The two 800 lb. gorillas in the room appear to be the butrans and/or gabapentin, and since the problematical effects seem to be abating, this (hopefully) won't be an issue for very much longer anyway.

Doc