Yes, it is working divided up. Some afternoons I forget to take it...but I am averaging 5 times a week so far. I don't get that tense thing when dividing the dose over the day. I take it around 4pm way before dinner.

My biggest problem has been sleeping and pain. I tried Elavil in 10mg dose, and it seemed to work for a week, then stopped...then my blood sugar went up..and I found that some new studies show effects on blood sugar for diabetics (due to some neuroendocrine thing--unexplained further). So I stopped it and my sleeping became broken again.

Now I am doing L-tryptophan again, and I have to say...it is really nicely working. People on SSRIs or things like Cymbalta cannot do this, but since I am not medicated that way, and it has been over a month on Elavil for one week...I can safely do it. I had a bottle left over from last year of 500mg NOW brand. I finished that off and replaced it with Doctor's Best...and wouldn't you know it! It is dynamite! This is the 3rd supplement I've found better at Doctor's Best. Theanine, from Swanson's was disappointing, and now the R-lipoic, and tryptophan. The kitten and Weezie make alot of noise at night playing sometimes, and it also wakes hubby up. So we both are using the tryptophan with great success. In fact we even got equal hangovers from the new one! So I am breaking them in 1/2 so we get 250mg each. I have some empty taurine caps from Oreo which I saved and that is how I do it, for now.