Abby, You might also want to consider that Mestinon may be acting on some muscles - like the ones that aren't that bad - but not acting on the ones that are really bad. So it may not seem like it's working but, in reality, it is. And you can't take more because more isn't necessarily better and may overdose the muscles that are doing better.

What happens if you take a Mestinon "holiday" and then take it again? Have you been on it and then gone off of it?

I always give this example because everyone has had pain. If your back hurt a little bit and you had a raging headache, acetaminophen may make your back better but not your headache. Except that with Mestinon, more isn't better. Neither would acetaminophen for a migraine. So you have to switch it up and use a different treatment, like IVIG for MG or Imitrex for migraines.

I don't have an answer for you, other than that. And Mestinon doesn't work for everyone but that doesn't mean you don't have MG. Crazy confusing disease, eh?

Annie