Quote:
Originally Posted by mrsD
Dr. Jay Cohen, believes that many drugs are used in too high of doses.
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I've been saying
that for some time (long before these examples), but phrased slightly differently:
Quote:
I agree with this for the same reason and another - that we should always take the least amount of anything required to acheive the desired results. Dosages are usually determined/recommended by the pharmaceutical companies based on averages derived from their studies/trials. Doctors tend to follow these guidelines unless they have experience/reason not to. But this also means "one-size-fits-all" medicine, and since we're all different, those guidelines are going to be too much for some and too little for others (which is my main argument for titrating from lower to higher).
http://neurotalk.psychcentral.com/post839119-21.html
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I won't argue that this has been intentional, and even misleading, in some cases, like the highly publicized Oxycontin case,
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In May 2007 Purdue Pharma "agreed to pay $19.5 million" in fines relating to aggressive off-label marketing practices of OxyContin in 26 states and the District of Columbia.[57] In specific, the company encouraged dosing more frequent than the recommended interval of 12 hours, and did not fully disclose the risk of hazardous or harmful use.
http://en.wikipedia.org/wiki/Oxycodo...nd_misbranding
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but I think it more likely
began in the attempt to find average dosing recommendations for doctors who aren't well-versed in pharmacology.
Doc