Mine started when I realized my foot wasn't getting any better, then I discovered it was the RSD monster. I held out for a year until I couldn't work anymore, then I felt completely helpless and felt like a burden to my spouse. That's when I knew and cried to my doctor, that I felt like I was worthlesss. They started me on abilify and it has dramatically improved my self worth. I still have my bad days when the pain is out of control, but I know that it will pass. So I throw my little temper tantrum and move on.