Misery loves company... so true with PD! I am rather late in replying, but CR is wicked. At first you get a little extra mileage, but it seems to have a build up effect in your bloodstream, so there is always a store or cached inside. I started getting very uncomfortable dyskinesia every afternoon. It sneaks up on you. The 25/100 CR is not enough to keep one going so we have to supplement with a regular one than have too much dopamine. I stopped when I realized I had to take more drugs than usual just to keep me going on the CR. Plus I have not heard a neuro say one nice thing about it.

That being said, it must work for some people, but i have yet to meet anyone.

Laura