I was on neurontin for over 10 years. Over this time I was advised by 3 different doctors as to what amount to take--all opinions differed. I never felt that it was monitored properly for side effects, no one ever checked metabolic levels or warned about what problems it might cause, and I always wondered how they came up with the dosages that they did. At one time it was too high and I had problems with feeling thick headed and almost slurring my words. The thing that I wasn't told was that a lot of antiseizure medications can wipe out vitamin B in your body and I ended up with a B12 deficiency. One of my friends who still takes one of those drugs takes a B-complex as well. I finally got off of the drug because I heard some things about lawsuits and it being toxic. I know that it works for some people, and that's great, but personally I would be concerned about taking a high dose for a long period of time. Right now I am working with a nutritionist and am off of all pain meds.