I would just be hesitant if you are going to take this medication. I have been on both amitryptiline and topamax. At first the Topamax seemed to do wonders for me, and my headaches decreased substantially. However, it only worked for a short amount of time, and as they increased the dose I began experiencing the side effects. On the medication I had serious memory loss, and could not bring up words when I wanted to. You should keep a diary, if you start experiencing anything weird write down the first time it occurred (time, symptom, severity, and frequency). If it is bad immediately call your doctor.
I hope everything works out, and your headaches go away. Feel Better