I have been tempted with wine on occassion, and with my medications it is a no no. so, I have had just one glass on superbowl sunday. I don't want the drink to interfer, so I really try not to. I am too afraid of the interactions, so I hold my self back from drinking very much. I had been use to one glass of wine on occassion, but since the meds started, I have complied for the most part. ginnie