I have the personal acquaintance of 2 men who have begun LDN therapy for PD Jan 2007. Both report that they were able to reduce their other medications, and have better energy, but this is still early.

We at least have the interest of NIH, and Dr Hong will be attending the NIH meeting on LDN April 20th.

From http://ldninfo.org/ldn_latest_news.htm
Research on Neurodegeneration Suggests a Protective Naltrexone Role. J.S. Hong, Ph.D., head of the Neuropharmacology Section of the Laboratory of Pharmacology and Chemistry at the National Institute of Environmental Health Sciences (NIEHS), finds that "morphinan" drugs, including naltrexone and naloxone, are able to reduce inflammatory reactions in microglia brain cells in animal studies. Such inflammation is believed to be central to the progressive neurodegenerative effects seen in disorders such as Parkinson’s disease and Alzheimer’s disease. Hong’s report, summarizing the role of microglia in inflammation-related neurodegeneration and the potential of therapy using morphinans, will appear in a January 2007 issue of Nature Reviews Neuroscience.

My experience is using LDN for MS, and a trial has now started at UCSF to investigate its effectiveness for MS. Details at http://LDNers.org
SammyJo