I don't think the PEG works orally for PN.... If you check those studies carefully...I would like to see the links in fact...
That PEG was injected into the tissue. And it does not say how much etc.
example:
Quote:
Acta Biomater. 2012 Jan 25. [Epub ahead of print]
Semi-interpenetrating network of polyethylene glycol and photocrosslinkable chitosan as an in-situ-forming nerve adhesive.
Amoozgar Z, Rickett T, Park J, Tuchek C, Shi R, Yeo Y.
Source
College of Pharmacy, Purdue University, 575 Stadium Mall Dr., West Lafayette, IN 47907, USA.
Abstract
An ideal adhesive for anastomosis of severed peripheral nerves should tolerate strains imposed on rejoined nerves. We use blends of photocrosslinkable 4-azidobenzoic acid-modified chitosan (Az-C) and polyethylene glycol (PEG) as a new in-situ-forming bioadhesive for anastomosing and stabilizing the injured nerves. Cryo-scanning electron microscopy suggests that the polymer blends form a semi-interpenetrating network (semi-IPN), where PEG interpenetrates the Az-C network and reinforces it. Az-C/PEG semi-IPN gels have higher storage moduli than Az-C gel alone and fibrin glue. Nerves anastomosed with an Az-C/PEG gel tolerate a higher force than those with fibrin glue prior to failure. A series of ex vivo and in vitro cell experiments indicate the Az-C/PEG gels are compatible with nerve tissues and cells. In addition, Az-C/PEG gels release PEG over a prolonged period, providing sustained delivery of PEG, a potential aid for nerve cell preservation through membrane fusion. Az-C/PEG semi-IPN gels are promising bioadhesives for repairing severed peripheral nerves not only because of their improved mechanical properties but also because of their therapeutic potential and tissue compatibility.
Copyright © 2012. Published by Elsevier Ltd.
PMID:
22310507
[PubMed - as supplied by publisher]
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This is a topical application, not oral.
This one also "applied" to both ends of cut nerves in animals.
http://www.ncbi.nlm.nih.gov/pubmed/22302626
This complicated paper uses a PEG film applied to the
surgical wound area:
http://www.ncbi.nlm.nih.gov/pubmed/20421076
So taking Miralax is not going to provide any nerve healing.
It is not absorbed mostly. The huge molecule is too large.
However in some adults a tiny portion may be absorbed. It seems that children have more of an issue with this problem than adults.
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Weezie looking at petunias 8.25.2017
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