View Single Post
Old 02-17-2012, 02:38 PM
en bloc's Avatar
en bloc en bloc is offline
Senior Member
 
Join Date: Feb 2011
Location: Shenandoah Mountains, VA
Posts: 1,250
10 yr Member
en bloc en bloc is offline
Senior Member
en bloc's Avatar
 
Join Date: Feb 2011
Location: Shenandoah Mountains, VA
Posts: 1,250
10 yr Member
Default

Quote:
Originally Posted by mrsD View Post
Yes, I like that drug checker too.

If anything it gives lots of moderate interactions.

Cardizem, as a hint, is a common interactor too.

Quinidine, cimetidine, coumadin, digoxin, carbamazepine are often tested against in drug applications today. So their inserts list interactions with them.

But those are not by far the only problematic ones. Cardizem is one. But the liver enzyme information is huge today compared to only years ago. Most doctors don't consult it at all IMO.
They wait for the pharmacy to catch it. And many pharmacists just blow away and override the moderate interactions or yellow flags. There can be SO MANY of these a day, one cannot call all those doctors and service patients in the same day anymore. That is no excuse, but there are SO MANY flags these days..you can't imagine.

Yes, that Cardizem is a problematic one for sure. Last July had a similar reaction (fighting for excretion and compounding potency in the process) with Cardizem and Biaxin (for acute thrombophlebitis that got infected). I found out this combo is a huge no-no and never should have been prescribed. An ER doctor did it and later apologized after finding out what happened. The pharmacy did catch it and called the doctor before filling. Doctor didn't think it would be that bad and confirmed the order. What idiots!! It's like a huge overdose of Cardizem (and compounded with an OD of Ranexa in this last case). Very dangerous...life threatening, in fact. Luckily I have a pacemaker (it will dramatically drop the heart rate), but still had very severe symtpoms and barely stayed conscious.

I research all my meds but never could find a good interaction tool like this one. EVERYTHING will be run through it from now on.

Are all calcium-channel blockers (like Cardizem) this problematic?
en bloc is offline   Reply With QuoteReply With Quote