[I have been taking Mertazapine (Remeron) in different dosages for years as an anti-depressant. Sometimes alone, sometimes with other drugs. When I'm doing well (not stressed out from work generally), it seems to help keep me on track. When I allow myself to get stressed out, I've taken it in addition to Seroquel, Effexor and others for defined periods of time to get back under control. I have GAD as well and take alprozolam as needed for attacks.

The mertazapine (for me, a mid fifties reasonably active male in pretty good shape) has has relatively no sleep impacts, little impact to diet cravings (over or under eating) and has minimum sexual side effects. Overall, good benefit to me.

I have no experience with the other drug.