Been quite a while since I've been on here! Background- 2007 TKR went bad, resulted in RSD in knee. Early 2008, diagonsed with Multiple Sclerosis and Ankylosing Spondylitis. Also have Osteoarthritis, Scoliosis, Hypothyroidism and Endometriosis. Yes, almost everything but the kitchen sink! My RSD has been confined mainly to my right leg (started in knee, then spread to leg and foot). But in the last six months, my right side of face goes bright red, swells, feels extremely tight like windburnt. My right forearm is also the same way. I am getting very nervous as the burning feeling is starting to effect my right eye. My eye burns and hurts when this acts up with is becoming more often, usually 3-4 times a week - can last over 24 hours each time. Can anyone give me your insight of RSD effecting your face as such and eye? I have had blocks done in the past for my leg which helped some but was left as that. I take Lyrica, Cymbalta and Methodone. What can they do medically for RSD effecting the face and eye? I am assuming its the RSD, but having the MS and AS, I'm not sure if these diseases can effect your face this way. I've got so much going on with my body, I did not need this to start getting worse - ugh! Thanks for listening and commenting.