Quote:
Originally Posted by fmichael
Hi. Sorry to be late on this, but I've been given something that's nothing short of awesome for flairs.
In addition to the backdrop of Oxycontin/oxycodone, Xanax and Baclofen, I've been using - as discussed here months ago - Neudexta, a combination of 20 mg of dextromethorphan HBr (DM) and 10 mg of quinidine sulfate. DM - widely used as an over the counter cough suppressant - just happens to be a powerful NDMA-receptor antagonist, second only the ketamine. Its downside in pain relief is that it's quickly metabolized by the liver. But, it turns out that quinidine - widely used in substantially larger doses years ago as a tricyclicate antidepressant before it was found to cause cardiac arrhythmia in too many people - completely blocks the metabolism of DM, for 4 - 6 hours at a time. To which my doctor adds a prescription for compounded DM in capsules, 30 mg each. (While Neudexta is covered by my insurance, DM is not, but its pretty cheap: 60 capsules costs $56.)
So, with the worst of flairs, as I was having a few minutes ago, I just take the foregoing - including 90 mg of DM - and I'm right as rain, and heading out to see a movie in few minutes!
One note of caution: even with only 10 mg of quinidine, Neudexta is contraindicated for anyone throwing a "long Q - T interval" on their EKG. So "pre-clearance" from your internist is a good idea.
I hope this is useful.
Mike |
Mike.
Thanks for the information on the Neudexta. I am feeling much better except for the pain in my foot. What started me thinking it was a serious flare which I really haven't had since pre-ketamine Jan2009 was the pain in my foot. My RSD is upper extremety right side. I have not had spread like this and it does concern me. It is a typical RSD type pain, burning, speads at times up my angle and one night up to my knee. I thought it might be my back, I do have some back issues but have responded to epidurals wonderfully and haven't had to have one it will be 2 years in April.
To sum up my PM Doctor thinks it's was a flare from Stress. My husband and I are caring for his terminally ill Mom. Stage 4 lung cancer. She wants to be home and we are trying to keep her there. We have help from Hospice but they are not there all the time and we live an hour plus from her. So it's a lot of running, coordinating with nurses, aids blah, blah, blah...One of us are there everyday, and his cousin has just commited to 1 day on the weekend. But we work, I only work PT, we have 2 children older, 21 and 17, but still live at home and it's just constant.
Thanks again everyone.
Gabbycakes