So I have really been trying to find out if these side effects are related. I just started lyrica for partial seizures. I also have R/A. My doctor thot that it would be great for both probs. however I have been trying to figure out if a person can have side affects almost instantly? I am starting out with only 25mg lyrica a day with gradual increase Is it possible to have a rash and itchy skin, and nightmares the same night you just started taking this drug? My neurogist said its is not possible. I don't want to over react but guess I don't understand why he said its impossible to have side effects this quickly. Has anyone had itchy skin and nightmares so quick after starting lyrica?