I'm not a chemist or pharmacologist, so I cannot explain the reasons myself. At first, I assumed the same as you, that 300 mg would be what's required, but it's not. The stabilized form had nothing to do with it; 100 mg. of regular RLA works as well as 600 mg of ALA, though some people do take more.

I do recall digging the info out of threads here, and following up on the web, even if I didn't understand it entirely. I'm on my first month of the stabilized form now (had to use up supplies of regular RLA) but I have not personally noted any difference over regular RLA as yet.

I started RLA over a year ago now, and it has been near-miraculous in my case (results may vary considerably). The stuff stopped my burning/pins & needles pain from PN within 48 hrs, and progression of the condition has stopped as well (but I cannot say for certain the RLA is responsible for that - it could be a number of factors).

Doc