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Old 03-13-2012, 08:02 PM
Mark in Idaho Mark in Idaho is offline
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Mark in Idaho Mark in Idaho is offline
Legendary
 
Join Date: Feb 2009
Location: Somewhere near here
Posts: 11,427
15 yr Member
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Getting some cognitive improvements is a worthwhile goal. Those improvements from use of a drug such as Aricept would likely be temporary.

There is little evidence the Aricept (donepezil) helps with concussion. It's use is in delaying or slowing the progression of AD.

Donepezil hydrochloride is postulated to exert its therapeutic effect by enhancing cholinergic function.

The question could be asked, Would getting the brain healthy with nutritional supplements be as effective or more effective, especially in creating a lasting improvement without the need for medication. Does the action of Aricept become a crutch that prevents the brain from re-establishing proper chemical balance.

The contra-indications of concomitant use of other meds puts some severe limitations on treating other symptoms, especially NSAID pain meds and nutritional supplements. This is in addition to the side-effects that are similar to the common cluster of PCS symptoms.

The NIH web site states: <Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antihistamines; aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); bethanechol (Duvoid, Urabeth, Urecholine); carbamazepine (Tegretol); dexamethasone (Decadron, Dexone); ipratropium (Atrovent); ketoconazole (Nizoral); medications for glaucoma, irritable bowel disease, motion sickness, myasthenia gravis, Parkinson's disease, ulcers, or urinary problems; phenobarbital (Luminal, Solfoton); phenytoin (Dilantin); quinidine (Quinidex); and rifampin (Rifadin, Rimactane). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

tell your doctor if you have or have ever had gastrointestinal (GI) bleeding; an ulcer,asthma, or obstructive pulmonary disease (chronic bronchitis or emphysema), or heart disease.

tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking donepezil, call your doctor.

if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking donepezil.>

Could this be simply a "Try this and see if it helps" shot in the dark?
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