I do know that Mestinon causes me to be nervous and gives me the shakes sometimes, as if I drank too much coffee.

I have looked for information about this as a side effect and can find no information.

I am very sensitive to medication in general, so maybe I was getting too much Mestinon. I reduced the amount until I only took 1/8 of a pill at a time and that helped a lot, but didn't completely eliminate the nervousness, just made it tolerable.

For me, since I have PTSD, maybe Mestinon somehow triggers PTSD and makes me nervous, although I don't know how. I only know how I react to Mestinon and if my MG is bad, it is worth it. I'd rather be nervous than unable to move.

I do think Mestinon is safe to take. I don't notice any permanent problems, just the nervousness and shaking about 15 to 30 minutes after taking Mestinon, and it goes away usually within an hour.