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Old 04-06-2007, 03:25 PM
Lara Lara is offline
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Join Date: Sep 2006
Posts: 10,984
15 yr Member
Lara Lara is offline
Legendary
 
Join Date: Sep 2006
Posts: 10,984
15 yr Member
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Hi wasabi, part of getting to a diagnosis of TS would be to rule out secondary causes. There are also many primary neurological conditions which manifest tics.

A diagnosis of Tourette's Disorder as stated in DSM IV-TR

e.g. "• the disturbance must not be due to the direct physiological effects of a substance (e.g. stimulants) or a general medical condition (e.g. Huntington's disease or postviral encephalitis)."
_____________

MEJIA, Nicte ; JANKOVIC, Joseph.
Secondary tics and tourettism
Rev. Bras. Psiquiatr.,
São Paulo, v. 27, n. 1, 2005.
http://www.scielo.br/pdf/rbp/v27n1/23707.pdf
for some reason that pdf won't load for me this morning. Here's the same thing in html... sorry about the keyword highlights. http://72.14.253.104/search?q=cache:...ient=firefox-a


Is it a tic or Tourette's?
Clues for differentiating simple from more complex tic disorders
Virgilio Gerald H. Evidente, MD
http://www.postgradmed.com/issues/20...idente_tic.htm

Quote:
Several conditions, termed tourettism, may mimic Tourette's syndrome. Drugs, including stimulants, levodopa (Dopar, Larodopa), and antiepileptic medications (eg, phenytoin [Dilantin], carbamazepine [Atretol, Epitol, Tegretol], lamotrigine [Lamictal]), may cause tourettism. Discontinuation of the offending drug leads to prompt remission of the tics. Neuroleptic medications with potent dopamine2 (D2) antagonist activity (eg, haloperidol [Haldol]) may cause tardive tourettism, which presents with delayed and often permanent tics identical to Tourette's syndrome.

Other causes of tourettism include infections (eg, Creutzfeld-Jakob disease, encephalitis), toxins (eg, carbon monoxide), Huntington's disease, head trauma, stroke, neuroacanthocytosis, chromosomal abnormalities, cerebral palsy, neurocutaneous syndromes, and schizophrenia
Recognition and Management of Tourette's Syndrome and Tic Disorders
MOHAMMED M. BAGHERI, M.D., JACOB KERBESHIAN, M.D., and LARRY BURD, PH.D.
http://www.aafp.org/afp/990415ap/2263.html

Secondary Causes of Tic Disorders

Quote:
Primary neurologic disorders manifesting tics

Acquired
  • Head trauma
  • Encephalitis
  • Stroke
  • Sydenham's chorea
  • Carbon monoxide poisoning
  • Creutzfeldt-Jakob disease
  • Neurosyphilis
  • Hypoglycemia

Genetic
  • Huntington's disease
  • Neuroacanthocytosis
  • Hallervorden-Spatz disease
  • Idiopathic dystonia
  • Duchenne's disease
  • Tuberous sclerosis
  • Chromosomal disorders
  • Down syndrome
  • Klinefelter's syndrome
  • XYY karyotype
  • Fragile X syndrome

Primary neuropsychiatric
disorders manifesting tics
  • Schizophrenia
  • Asperger's syndrome/autism
  • Mental retardation
[These lists don't include everything. Wilson's Disease is also a disease where the patient might present with tics. There have been other medications implicated over the years in individual patients and also lightning stike. I remember we used to have a forum member years ago whose son was eventually found to have a brain tumour which was causing the tics. Also, to confound all this, some people with say Asperger's Syndrome or Autism may also have tics, but a small percentage can actually have Tourette Syndrome as well. There is a LOT of information available about this subject if you need any more.]

p.s. [Remember the book called Awakenings, by Oliver Sacks? It was also made into a movie. Well the illness that those people had was a type of encephalitis called Encephalitis Lethargica and motor and vocal tics as well as compulsions were reported in those patients... that was way back in the early 1900's].

Last edited by Lara; 04-06-2007 at 04:46 PM. Reason: edited about 15 times lol... uh oh, make that 16
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