I suffered with serious depression for decades before Parkinson's diagnosis. When I began taking the "gold standard" medication carbidopa/levodopa I experienced greater relief from depression than with any previous combination of antidepressant meds and/or talk therapy.

I currently take Buproprion (generic Welbutrin) and Cymbalta to help keep my mood positive, along with a total 1100mg of combination controlled release and fast-acting carbi/levo, along with amantadine.

I am in my 11th year of PD diagnosis. My PD is of the primarily bradykinetic, balance challenged type, with essentially no tremor. I do experience "on-off" effects if my meds timing is not spot on, but mostly maintain good mobility and fairly good strength and energy, and only minor dyskinesia and dystonia.