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Old 04-03-2012, 10:54 AM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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mrsD mrsD is offline
Wisest Elder Ever
mrsD's Avatar
 
Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
Lightbulb

There is a difference between folic acid and folate.

Folic acid is synthetic and may compete with natural folate at
the blood brain barrier, and this may cause problems.

Folic acid is methylated thru a system called the MTHFR reductase system, and if you have a genetic error in DNA (which is not rare---10-30% may have it) you cannot activate B12 either or folic acid to their active forms in the body.

http://advances.nutrition.org/content/3/1/21.abstract

http://www.plosone.org/article/info%...l.pone.0024976
(this article shows folic acid is not active.)

http://www.ajcn.org/content/87/3/517.long

These articles were sent to me by poster here, Karsten.

You can see it is a complex subject, and hence even doctors will
have some difficulty answering your questions, and/or interpreting the test results.

I'd consider getting the DNA polymorphism test to see if you can activate/methylate properly. This typically runs just over $100 without insurance.
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