Brain Vitale

Are you wondering what you can do to keep your brain healthy, boost your energy and
focus and enhance your memory? Dr. Daniel Amen, New York Times bestselling author
of “Change Your Brain Change Your Life” and “Preventing Alzheimer’s” has developed
Brain Vitale, a combination of powerful antioxidants and nutrients essential in protecting
brain health. Brain Vitale contains a proprietary herbal blend of ginko biloba extract
which has been clinically proven to enhance cerebral blood flow and improve brain
function.

We recommend Brain Vitale for those looking to enhance overall brain health,
circulation, memory and concentration. This is an excellent supplement to incorporate in
your regimen to keep your brain young and healthy.

Background

Acetyl-L-Carnitine (ALC) -- It is involved in cellular energy production and in
removing the toxic accumulation of fatty acids. It functions to increase energy in the
brain which helps to enhance memory and concentration. Acetyl-L-carnitine has been
most studied for its anti-aging properties and research supports the use of acetyl-l-
carnitine to slow the decline in cognition, mood, and daily function that occurs with the
progression of Alzheimer’s disease (Ref.3,4,5).

A major cause of aging is deterioration of the energy-producing components of your
cells, resulting in reduced cellular activity, the accumulation of cellular debris and
eventually cell death. ALC helps maintain cellular energy metabolism by assisting in the
transport of fat through the cell membrane and into the mitochondria within the cell,
where fats are oxidized to produce the cellular energy ATP.

ALC is found in the mitochondria and helps maintain its energetics and lowers the
increased oxidative stress associated with aging. ALC are absorbed into the bloodstream
efficiently and is effective at carrying fatty acids across the membrane into the cell where
they are burned as energy and utilized efficiently by the mitochondria. ALC also guards
against oxidative damage. Beta amyloid is a principal component of senile plaques and is
thought to be central in Alzheimer’s disease. ALC appears to exert protective effects
against beta amyloid neurotoxicity and oxidative stress.

Phosphatidyl Serine is a lipid essential to the formation of all cell membranes.
Naturally, it is found in fish, soy and white beans. It functions to increase metabolic
activity and has been shown to help prevent cognitive decline. It is a critical component
to brain health and supplemental phosphatidylserine has been shown to help prevent
Alzheimer’s disease (Ref.42)

GlyceroPhosphoCholine is a component of lecithin (a lipid) that is important in the
breakdown and removal of fats from the body. Not only does it protect the heart from

atherosclerosis by helping to remove plaques, it aids in brain function. In supplement
form it has been shown to be effective for people with neurological issues and
depression.

Inositol is a natural sugar that is considered part of the B vitamin family. It is important
in the maintenance of cell membranes, breakdown of fat, hair growth, estrogen and
insulin regulation and has been shown to modulate serotonin levels, which implicates this
nutrient as a potential mood regulator. Preliminary studies demonstrate its efficacy in
treating those with OCD, panic disorder, anxiety, depression and psychiatric disorders
(Ref.23,33,41). It also functions to neutralize free radical activity, thereby protecting
neurons and promoting brain health.

Ginkgo Biloba is an extract from the ginkgo biloba tree, native to China, which is most
recognized for its neuroprotective, antioxidant properties. It is commonly recommended
for people who have dementia, low cerebral blood flow or those experiencing cognitive
decline. It functions to improve blood flow to the brain and to protect neurons from
plaque formation. Promising research studies (see below) have reported that
supplementation with ginkgo biloba results in enhanced memory and concentration, and
therefore it is used as a preventative measure for Alzheimer’s disease. Most recently, it
was studied in children with attention-deficit disorder and was found to successfully
reduce the hyperactivity and irritability with no side effects (Ref. 1). Some side effects
associated with ginkgo biloba may include gastrointestinal distress, nausea, vomiting,
diarrhea but numerous studies have shown it to be safe (Ref. 1,2,9,14,16-17) . If you are
pregnant, on warfarin therapy, blood thinners or are taking antidepressants, consult with
your physician to see if ginkgo biloba is right for you.

Scientific Studies

Ginkgo biloba has been studied at length as a natural way to improve the cognitive
function of those with Alzheimer’s disease (Ref. 11,12) There has been promising
evidence of the effectiveness of ginkgo biloba on preventing cognitive decline (Ref. 10-
15,18,22-25,27-28,30,32,34-36,38-40), neuronal protection (Ref. 35) and reducing
neuronal plaque formation (Ref. 15). While there is continued controversy of its efficacy
(Ref. 2,6-8), there is robust evidence in the literature in support of ginkgo biloba for
enhanced circulation to the brain, protection from free radical damage and preventing the
deposition of plaques.

As a dietary supplement, take one to two capsules of Brain Vitale per day with meals or
as directed by your healthcare professional.

“The prettiest brains I have seen are those on gingko.” Dr. Daniel Amen, Making A Good
Brain Great