Now how does taking any of these on a empty stomach affect your stomach, does it cause any stomach issues. I'm already on nexium for acid reflux so I'm not sure if i need to take it before or after i take my Nexium. Nexium blocks the stomach from absorbing lots of things and I've often wondered if it is not the problem when I"ve had low Vit D as my body can't absorb due to the nexium blocking things i need. I think I won't try the all in one wonder pill just didn't know about it . Thanks for all the really really good advice .