@Kenjhee

It has been known for quite some time that the damage done to the brain is more than just diffuse axonal injuries.

The metabolic cascade mentioned by the article is happening directly after the head injury and continues to do damage in the weeks following recovery.

In the past people believed that this was completely reversible and had no permanent effect on the brain. Furthermore it was believed that no structural damage was done to the brain when having a concussion.


Today we know this not to be true. The damage can be split up in three main categories which can all be diagnosed with the right equipment.

Structural; DTI, MRI, CT

Metabolic; fMRI, SPECT, PET

Funktional; MEG, EEG, BAEP

Structural damage is macroscopic damage to the brain in white and gray matter areas.

Metabolic damage is damage to the brain-blood barrier, vasoconstriction/dilation of capillaries and damage to astrocytic cells.

Functional damage is the change in brain activity and electrical impulses in the brain caused by a disruption or change in action potentials.


These three kinds of damage are all interconnected on a deeper level. Metabolic damage results in changed brain activity and so on...

When we say that people suffer from PCS, we donīt talk about a specific kind of damage or underlying issue but a whole range of possible deficiencies in the brain. So diffuse axonal injuries are only part of the problem and not the entire

syndrome in itself. If only it was that easy

I hope this clears it up, if not, just ask away.

-GlassHead