I know the type of injections I'll not have again: Any TNF inhibitors. I've been through Remicade, Methotrexate, Enbrel, Humira and Simponi. Each time, I've had a horrendous adverse immunologic response. The latest took 8 months to clear my system. When my rheumatologist called, wanting to see me about it, I politely declined. There's no way I'm being injected with yet another medication that has the potential to cause me so many probs.