Is this a possibility?

For some types of PD and for some types of PwP, we already have treatments which radically slow down the progression of the disease? BUT, we don't know we've got them.

I'm thinking of the work by Jannetta on nerve compression, GDNF, exercise, supplements etc..

I'm thinking of the different rates of progression from person to person, which suggests that there is more than one disease process at work and that there are some theraputic regimes which are better than others.

If this is the case:
- track everyone, especially the long term survivers. What have they done differently?
- design clinical trials focussed on the individual: a drug which slowed progression by 50% for half of PwP but increased it by 50% for the other half would be a great drug ... provided you could focus it on the right group.

John