What test? There are many tests for AI diseases. Can you be more specific? Was it for SSA & SSB?

The lip biopsy is no big deal, really. There are some the get a very small area that is numb or has a lump. I have both but VERY small and certainly not worth complaining about. You are going to find people that have bad experiences with any test out there. Most don't have problems, but when you are reading online, you'll hear about the minority. Keep in mind that all those with good experiences are not going to post online just to say it was fine.

The lip biopsy is the definitive test. Up to 40-50% will be sero-negative for Sjogren's, so the biopsy is the way to go if you have other symptoms and want to confirm or deny Sjogren's. I have all negative blood work, but my lip biopsy clearly shows Sjogren's at end stage.

Have you had a Schirmer's test to determine if you tear production is abnormal?