My daughter is receiving her second round of IVIG infusions this week. After the 3rd dose she noticed that she felt moderate upper back pain. This is a dull, tight feeling. She is receiving pre-meds of solu-medrol and zofran, so she has kept the headache at bay, but this neck/back pain is the only complaint. Has anyone else heard about the reason for this? Could it be that the IgG antibodies in the IVIG are being pulled into the spinal fluid and causing spinal pain?