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Old 04-23-2012, 03:23 PM
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
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mrsD mrsD is offline
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Join Date: Aug 2006
Location: Great Lakes
Posts: 33,508
15 yr Member
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Originally Posted by Peony View Post
Thanks so much for your clear response, MrsD. I recently had testing with these results: Vitamin B12 was 908 pg/mL and Folate RBC was 658 ng/mL. My G.P. doctor says these are fine, but 23andMe forum participants say I may still need supplementation, esp. for folate, due to my MTHFR "compound heterozygous" status, but type, source, dosage were unclear. Sounds like I should also request homocysteine testing. Thanks again!
If you are not using methylB12 already, and had that test routinely for B12, and it measured other B12 in the serum not being converted... you could still be low in ACTIVE B12.

An MMA and/or homocysteine test will be high when B12 is not being utilized by the body correctly... and is more definitive for those who have the MTHFR mutation. There are several types of MTHFR also ,, which is beyond me, I am sorry to say.
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