hi
i have had Willis-Ekbom disease ( aka RLS ) since i was little and have been on requip sine it was approved for RLS treatment and has worked well most of the time. Like many others there are certain things that trigger it into high gear.
i recently started taking b12 and had to stop it got so bad nothing helped and i walked the floor for 2 days.I am now getting better and have stopped the b12.I was recently dx with small fiber neuropathy ( confirmed by skin biopsy). One of the first thing my neuro asked was did i have Willis-Ekbom disease. She then told me there has been some speculation of patients with sfn also having Willis-Ekbom disease. She said there was research going on in that area, so there may be a connection. I do know they have found a gene mutation for Willis-Ekbom disease and they are sure it can be passed in families (such is my case ) I don't know if this helps or not but there is a RLS org with much more info.