Lyrica worked MUCH better from me. The neurontin/Gabapentin really didn't do much for me at all whereas with the Lyrica it was definitely a noticeable difference. But everyone is very different. Sometimes finding the right combination of meds is the key. But if one of the symptoms is particularly bothersome then it may be worth it to try something new. Just make sure to taper on/off the meds. I had a few doctors that were putting me on and taking me off meds abruptly and it really messed me up big time last year and I ended up with seratonin syndrome in the midst of a whole bunch of new RSD symptoms. NOT fun. Always be careful with any meds you take.