I'm not taking mtx anymore. It was way too hard on my stomach/GI tract because I have Crohn's Disease on top of everything else, grrr. When I started on it, I did the injections but when the injectable was difficult to find, I switched to the pills.

I know I took 20 mgs. and it may have been raised to 25 mgs. at some point. It's been at least 5 years since I've taken it so I don't recall how that went. I just know that I didn't start that high -- my doctor started me on it at a much lower dosage and raised it over time.

Oh, and when I started it, my diagnosis was RA. Now we're not sure if it's Lupus with a scleroderma overlap or MCTD. I've tested positive routinely for Lupus and Sclero but didn't have the Sclero signs until the past 18 months or so.