Hi everyone. I'm new to this forum; was recently diagnosed with Small Fiber Neuropathy and today found out I tested negative for just about every potential cause (autoimmune diseases, diabetes, HIV, hepatitis, etc.).

It's good news, but I'm very confused, frustrated and anxious.

First off, let me say, my neurologist is fantastic--one of the top in his field at a fine hospital (NYU). He is extremely thorough and I trust his opinion.

I am a 40-yr-old female, in good health, about 20 lbs. overweight, but in reasonably good shape (worked out 3x a week until 2 months ago) and fairly healthy diet (no fast food or soda; lots of veggies, whole grains, lean meat).

A few years ago, I began experiencing numbness, tingling and burning in my feet. In 2011, I finally had an EMG & MRI. Results showed nothing. Then, earlier this year, the tingling and numbness turned to PAIN, so I had another MRI--this time it showed nerve damage & edema in both feet/ankles. Skin biopsies on ankle & hip showed Small Fiber Neuropathy.

I started on 300mg gabapentin in late April, now up to 1200mg. But it doesn't help w/ the pain and it makes me drowsy and foggy. I also have blurred vision, shortness of breath and short-term memory loss. And I feel physically exhausted ALL day (I walk with a cane & take the subway to work each day--lots of stairs!).

Now, my doc suggests I try Cymbalta, but I want to read more about it first. Also, he did say my B12 was slightly low, so I'll start taking 1000mcg a day.

Though I have my share of stress and anxiety, I'm happily married, have a good job, 2 cats and close-knit family. I'm generally a happy person, but after 2 months of pain and limited mobility, I'm sad, listless and indifferent. Part of it is not being able to exercise--that's my stress relief. Also, living in NYC, I'm used to walking EVERYWHERE and I miss it terribly. Now, I'm depressed most of the time. I feel like I'm missing out on everything, but at the same time, I don't want to take part in anything because I can't enjoy it.

I'm also horribly sad and frustrated because, after months of tests, we have not determined any cause for my pain and immobility. I'm overwhelmed by the notion that this pain could just continue indefinitely.

So that's my story. I'm considering acupuncture, homeopathic or dietary remedies (other than B12). I wonder if Cymbalta would help with depression or make it worse? Any advice or suggestions would be helpful!

Thanks for listening and be well...

APJH