I don't believe so. But I do think that if there are improvements when you are taking many things, it will be difficult to pin down what is doing what.

In this thread the original poster has a diagnosis of low B12.
That should be attended to first, to see if improvements occur with supplementing it.

For Idiopathic patients with no B12 deficiency then typically they are on some RX medications when they come here. And many times are not getting the relief expected. So adding in some supplements, may help and turn things around. It is easier to
spot these improvements, because they were stalled using what the doctors gave. Each case is somewhat unique, therefore.

People with terrible dietary habits or gluten intolerance, may be low in many things as well (magnesium, antioxidants, B1). And people with mito damage, may need the combos (CoQ-10 +Acetyl carnitine + lipoic acid) for improving mitochondrial functions.

These are examples, of why I tend to ask lots of questions...because the answers may point to a different approach for that poster.