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Old 05-27-2012, 07:26 PM
Idiopathic PN Idiopathic PN is offline
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Join Date: Jan 2012
Location: Jacksonville, FL
Posts: 793
10 yr Member
Idiopathic PN Idiopathic PN is offline
Member
 
Join Date: Jan 2012
Location: Jacksonville, FL
Posts: 793
10 yr Member
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Dear Mrs.D,
I was given 10mg 1x a day to be increased to 2x a day on the second week.
I understand that lower dosage of this medicine is intended for pain, but can it also improve the mood without increasing the dosage?

I am not sure Mrs. D but, I think my mood needs improvement. That is why I keep on taking SAM-e because aside from my arthritis which is really bothering me, I was hoping it can help my mood. but i notice that with the current dosage I am taking (200mg), I dont feel any change in my and instead I feel anxious. My plan was to increase the dosage so my arthritis can benefit more but with the nortriptyline coming in the picture, this will of course change.

By the way, thank you very much for advising me to stop SAM-e should I decide to take Nortriptyline. That was very thoughtful of you to advise me of the contraindication between the two. If I stop SAM-e, is there anything that you can recommend for my arthritis?

Mrs.D, as I mentioned in my earlier post, constipation is a problem to me now, Nilram warned me that constipation is one of hte side-effects of Nortriptyline, is taking virgin olive oil on daily basis safer than taking Metamucil, meaning that would it not affect the absorptions of all the drugs and supplements I am taking? As you know, with all my prescribed medicines and supplements, I have very little window for Metamucil.

Lastly (for now...), I understand that calcium affects the absorption of some prescribed medications, does it also affect the absorption of the supplements/vitamins?

Thank you so much.

Quote:
Originally Posted by mrsD View Post
I think insomnia is less likely than the reverse.

In antidepressant doses, the side effect profile is typically different than in the lower doses used for PN.

It can take up to a month to see effects.

When I tried amitriptyline (the parent compound) last winter I had pain relief within 3 days. But that wore off in the low dose I was taking after about 10 days. Because it made my blood sugar go up, I discontinued it. No sense in raising the dose etc, for me.

Nortriptyline is the active metabolite of amitriptyline (Elavil). So their actions are very similar.
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