IG is an individual case by case dosage/time schedule based on many variables including diagnosis, treatment response, symptoms, your weight in kg. With MG, unless in spontaneous or drug induced remission, we will have varying symptoms and possible breakthrough symptoms even while we are on treatments and well controlled. I take cellcept, prednisone, mestinon and 2 days IG every 2 weeks for the past 2 years and still have some occasional breakthrough symptoms. I just deal with the symptoms when they are there and am just thankful for the improvement I've seen. You need to have a very good working relationship with your neuro where there is a contunual exchange of your observations, progress and setbacks (and why you think they happened) and it will work for you. Good luck to you!