Hello
I am up to about three and a half years on Ty, and I have to say that although the cannula insertion can be a little yucky if they have trouble finding a suitable vein, there is no pain with the infusion.
As far as down-time goes, no problem at all. I just jump in my car and drive myself home straight after the infusion, and apart from feeling a little tired that night (which could also just be because I was tired anyway) I am fine.
One of the ED doctors where I go offers a little local anaesthetic if he thinks it might be a little tricky to get it in. He is my favourite
Good luck and let us know how you go
Cheers
Lyn