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Old 06-13-2012, 01:46 PM
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mrsD mrsD is offline
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mrsD mrsD is offline
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Join Date: Aug 2006
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Posts: 33,508
15 yr Member
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Incidence: Alpha 1-antitrypsin


http://www.ncbi.nlm.nih.gov/pubmed/12426287
Quote:
CONCLUSIONS:

The database presented indicates that in a total population of 4.4 billion in the countries surveyed worldwide, there are at least 116 million carriers (PiMS and PiMZ) and 3.4 million deficiency allele combinations (****, PiSZ, and PiZZ). Furthermore, this database demonstrates that AAT deficiency is found in various populations of African blacks, Arabs and Jews in the Middle East, whites in Australia/New Zealand, Europe, and North America, central Asians, far east Asians, and southeast Asians. These data demonstrate that AAT deficiency is not just a disease of whites in Europe, but that it affects individuals in all racial subgroups worldwide. In addition, AAT deficiency may be one of the most common serious hereditary disorders in the world.
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