Hi guys! Please give input regarding my trial. I've been taking 15mg of Mestinon twice a day, beginning Sunday June 10th. For a week, I can't say I noticed any effects, good or bad.

Yesterday (my 8th day into this trial) I took the morning dose, and half hour later became quite ill. I felt extremely woozy, dizzy/lightheaded, tired, a little weak, a little nauseated, and explosive diarrhea. It lasted a couple hours and then I felt much better. It was not unlike the effects I experienced when I took 60mg cold turkey.

Does Mestinon build up in one's system? I skipped the second dose yesterday. I took 15mg this morning with no effects at all. What might I conclude from yesterday's incident? How should I proceed with my trial? At what point do I decide if this is working or not?

I can't ask my doctor. The prescribing neurologist said he will prescribe therapeutic trials for me, but he's done treating me and doesn't want to see me anymore. My primary doctor is on maternity leave, so I can't ask her or get a referral to another neurologist started for another month or two.

Thanks for any help you can offer
Tatia