As you know botox is not permanent. So i did some researchs so find potential alternatives (but speculatives)

1) Botox + anti-igf1 or cfr

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053117/

2) Doxorubicin Chemomyectomy

http://www.vhlab.umn.edu/research/doxo.html

http://content.lib.utah.edu/cdm4/ite...jno&CISOPTR=84

http://onlinelibrary.wiley.com/doi/1...O;2-Y/abstract

http://www.iovs.org/content/42/6/1254.full.pdf

3) photochemomyectomy

http://www.ncbi.nlm.nih.gov/pubmed/1533899