Originally Posted by mrsD

Welcome to NeuroTalk:

I wonder in reading this history if your husband was given antibiotics in the fluoroquinolone family, or Flagyl? (there are others also less commonly used like Zyvox and Tindamax).

Fluoroquinolones can cause tendon damage and ruptures. The ruptures may occur up to a year or more after use of the drugs.
This family of drugs are also neurotoxic and can cause peripheral nerve damage and in the elderly can affect the CNS as well.
This is thought to be permanent, but Dr. Jay Cohen, MD thinks some supplements may work for it.


There are suggestions that use of steroids and/or NSAIDs with fluroquinolones may make the reactions worse.

The mechanism of this damage is not understood clearly yet.