Originally Posted by en bloc

I haven't seen much on diagnostics & testing, so hope this opens the door for discussion about what people have found helpful and what's new.

When it comes to PN, many different tests can be done to look for the culprit....sometimes (actually, many times) still without finding an answer. They can include EMG and nerve conduction studies, skin biopsy for small fiber neuropathy, sural nerve biopsy, and of course basic xrays and MRI's to check for mechanical/structural problems where nerves may be damaged as a result.

I have had all of the above over the years, but minimal findings here & there didn't account for the severe nature of my autonomic neuropathy and now more pronounced PN affecting proprioception, balance, mild sensory, and pain in the neck, back, legs, and bottoms of my feet.