I've had 3 courses of prednisone since my brain injury. 2 courses were 6 days long and the current one is a month long. I'm taking it for a skin rash of unknown cause.

When I'm on the prednisone, I have more energy (bordering on manic with high doses) and generally feel slightly better... my headache doesn't improve that much, but in general my body aches and pains are much lower, including neck pain.

At the higher doses I have a hard time sleeping and resting, but dont' seem to require as much rest so its ok. I also get a bit of heartburn with it, so I take another OTC drug, I can't think of the name.

Depending on the length of course you're on, it will be a tapering dose... I've found that every time my dosage decreases, I'm more tired and miserable. After a day or two at that dose, its slightly better again.

I'm sorry that's not more helpful.
Starr